METFORMIN

METFORMIN causes Vit B12 Deficiencies & Nerve Damages

Vitamin B12 is vital for the formation of red blood cells and for the proper functioning and health of nerve tissue. Vitamin B12 is a water-soluble nutrient. One of its most important functions is to build the red blood cells that carry oxygen throughout the body. Another function is in the nerves, where Vit B12 assists in the firing of nerves, sending important messages from the brain to the body. 

Since Vit. B12 is difficult to absorb many people have deficiencies and are not even aware of its effect on their health. It is important to note that the only sources of vitamin B12 are in animal and dairy products. So Vegetarians must add Vit B12 supplement to their diet regularly

Vit B12 deficiency can cause fatigue, low blood pressure, dementia, depression, muscle weakness, hallucinations, vision problems and tingling in the limbs. Some forms of dementia and Alzheimer`s disease are reversible with proper Vit B12 supplementation. Levels of Vit B12 just under normal can cause symptoms, even before symptoms of anemia are observed.

Vitamin B12 deficiency, if left untreated, can lead to anemia as well as nerve and brain damage, which may eventually become irreversible.

 

METFORMIN,  a popular drug (which is sold under the various Trade names, such as Glucophage, Glumetza, Glucophage XR, Fortamet etc) is  given to treat Type 2 diabetes and insulin resistance. It can cause Vit.B12 deficiency.

A recent survey found that 40% of metformin users were deficient in vitamin B12. Three-quarters of those metformin users also displayed the peripheral neuropathy typically found in diabetics. These findings were reported at the American Diabetes Association`s 69th Annual Scientific Sessions in June, 2009. This prompted a recommendation that anyone using Metformin who has peripheral neuropathy be screened for vitamin B12 deficiency.

Vit.B12 supplements can be given orally or by injection. Recommended dosage is 500 mcg. per day. A simple blood test can be used to diagnose a B12 deficiency. Those taking Metformin are advised to have their B12 levels checked.

Sources:-

http://www.hsph.harvard.edu/nutritionsource/...
http://www.webmd.com/a-to-z-guides/vitamin-b...
http://www.labtestsonline.org/understanding/...
http://diabetes.webmd.com/news/20090608/metf...

N.B:- Become SLIM without Exercising or Dieting